The GenomeZipper uses a novel approach that incorporates
chromosome sorting, second generation sequencing, array
hybridization and systematic exploitation of conserved
synteny with model grasses. It allows to assign 86% of the
estimated about 32,000 barley genes to individual
chromosome arms. A series of bioinformatically constructed
'zippers' integrate gene indices of rice, sorghum and
brachypodium in a conserved synteny model and assemble
21,766 barley genes in a putative linear order. The
genomeZipper files provide an ordered, information-rich
scaffold of the barley genome.
Mayer et al. Plant Physiol, 2009 Oct;151(2):496-505.